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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARHGAP1 All Species: 31.52
Human Site: S118 Identified Species: 63.03
UniProt: Q07960 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q07960 NP_004299.1 439 50436 S118 T L D Q Y V E S D Y T L L Y L
Chimpanzee Pan troglodytes XP_508398 562 63325 S241 T L D Q Y V E S D Y T L L Y L
Rhesus Macaque Macaca mulatta XP_001101907 504 57584 S183 T L D Q Y V E S D Y T L L Y L
Dog Lupus familis XP_851463 698 78707 Q286 V A R H G I L Q V A G E D R F
Cat Felis silvestris
Mouse Mus musculus Q5FWK3 439 50392 S118 T L D Q Y V E S D Y T L L Y L
Rat Rattus norvegicus NP_001101217 439 50604 S118 T L D Q Y V E S D Y T L L Y L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426422 437 50382 S119 T L D Q Y V E S D Y T L V Y L
Frog Xenopus laevis NP_001086509 435 50336 S119 T L D Q Y V E S D Y T L V Y L
Zebra Danio Brachydanio rerio NP_001017781 434 49569 S118 T L D K Y V E S D Y T L I Y F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VTU3 476 54951 N144 E I E P F V E N D Y I L V Y F
Honey Bee Apis mellifera XP_624226 496 56427 Q180 T L D T F V E Q D Y S L V Y F
Nematode Worm Caenorhab. elegans NP_001022390 444 50636 Q128 I I D K I V D Q D Y T I V Y F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.7 86.1 30.5 N.A. 96.5 94.5 N.A. N.A. 81 74.4 61.7 N.A. 33.1 43.5 37.8 N.A.
Protein Similarity: 100 77.9 86.3 42.8 N.A. 97.7 97 N.A. N.A. 89.5 86.7 75.1 N.A. 53.1 61.6 57.6 N.A.
P-Site Identity: 100 100 100 0 N.A. 100 100 N.A. N.A. 93.3 93.3 80 N.A. 40 60 40 N.A.
P-Site Similarity: 100 100 100 6.6 N.A. 100 100 N.A. N.A. 100 100 93.3 N.A. 73.3 80 73.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 0 0 0 9 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 84 0 0 0 9 0 92 0 0 0 9 0 0 % D
% Glu: 9 0 9 0 0 0 84 0 0 0 0 9 0 0 0 % E
% Phe: 0 0 0 0 17 0 0 0 0 0 0 0 0 0 42 % F
% Gly: 0 0 0 0 9 0 0 0 0 0 9 0 0 0 0 % G
% His: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 17 0 0 9 9 0 0 0 0 9 9 9 0 0 % I
% Lys: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 75 0 0 0 0 9 0 0 0 0 84 42 0 59 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 59 0 0 0 25 0 0 0 0 0 0 0 % Q
% Arg: 0 0 9 0 0 0 0 0 0 0 0 0 0 9 0 % R
% Ser: 0 0 0 0 0 0 0 67 0 0 9 0 0 0 0 % S
% Thr: 75 0 0 9 0 0 0 0 0 0 75 0 0 0 0 % T
% Val: 9 0 0 0 0 92 0 0 9 0 0 0 42 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 67 0 0 0 0 92 0 0 0 92 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _